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Tests on mice have shown that the hormone activates genes that turn white fat into beige fat that can be converted into energy
The 'exercise hormone' is not a myth - it actually exists, according to scientists.
Irisin is a chemical that circulates ion the blood and increases as a person exercises.
The discovery by Harvard University researchers could led to an obesity drug.
Tests on mice have shown that the hormone activates genes that turn white fat into beige fat that can be converted into energy.
The findings could also have an impact on diabetes, heart disease and cancer.
The research was published in the journal Cell Metabolism.
Professor John Yates of The Scripps Research Institute, who was also not affiliated with the work, said: "Spiegelman and colleagues have unequivocally shown that the mythical irisin peptide is produced as a result of exercise.
"This data should settle the controversy surrounding the existence of irisin and its increase in blood as a function of exercise."
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