x Health Men's Health Children's Health Nutrition and Wellness Reproductive Health Health & Science Digital News Videos Opinions Cartoons Education E-Paper Lifestyle & Entertainment Nairobian Entertainment Eve Woman Travelog TV Stations KTN Home KTN News BTV KTN Farmers TV Radio Stations Radio Maisha Spice FM Vybez Radio Enterprise BULK SMS E-Learning Digger Classified The Standard Group Corporate Contact Us Rate Card Vacancies DCX O.M Portal Corporate Email RMS
Login ×
BTV
VAS
DCX
RMS

US firm says coronavirus test working

Health & Science - By Anyango Otieno | May 20th 2020 at 12:00:00 GMT +0300
A sign marks the headquarters of Moderna Therapeutics, which is developing a vaccine against coronavirus in Cambridge, Massachusetts on May 18, 2020. [Reuters]

A vaccine manufacturer is reporting preliminary data suggesting its Covid-19 (mRNA-1273) vaccine is safe, and appears to be eliciting in test subjects an immune response capable of preventing disease.

Volunteers who received Moderna’s Covid-19 vaccine had positive early results, according to the biotech company, which has partnered with the US government’s National Institutes of Health to develop the vaccine.

On its website, Morderna, which is based in Cambridge, USA, said in a statement dated May 18 that the early data came from the phase I clinical trial, which typically studies a small number of people and focuses on whether a vaccine is safe and elicits an immune response.

“If future studies go well, the company’s vaccine could be available to the public as early as January,” said Tal Zaks, the chief medical officer at Morderna.

The Moderna vaccine is made using messenger RNA, or mRNA, a molecule containing the genetic instructions to make a protein on the coronavirus surface that is recognised by our immune systems.

“These interim Phase I data, while early, demonstrate that vaccination with mRNA-1273 elicits an immune response of the magnitude caused by natural infection, starting with a dose as low as 25 (microgram),” said Dr Zaks.

He added: “When combined with the success in preventing viral replication in the lungs of a pre-clinical challenge model at a dose that elicited similar levels of neutralizing antibodies, these data substantiate our belief that mRNA-1273 has the potential to prevent Covid-19 disease and advance our ability to select a dose for pivotal trials.”

The company reports no serious side effects. However, modest side effects included redness at the injection site, headaches, fever and flu-like symptoms, although none of these lasted more than a day.

The first 45 volunteers for the vaccine trial were divided into three groups, with each group getting a different dose of the vaccine. All groups got an initial shot, followed by a booster shot a month later.

The US Food and Drug Administration (FDA) has given Moderna the green light to begin a phase II study expected to enrol an additional 600 volunteers – half older than 55 – to provide additional immunogenicity data.

The company hopes by July to begin a phase III study, aimed at showing that the vaccine can actually prevent disease.


Coronavirus Test Covid19

Top Stories

Hospital swamped as patient numbers swell
Health & Science - By Mercy Kahenda


139 test Covid-19 positive as cases near 100,000
Health & Science - By Betty Njeru


NMS recruits 600 nurses as it prepares to open four hospitals
Health & Science - By Josephat Thiong'o


Africa's COVID-19 case fatality rate surpasses global level
Health & Science - By Reuters


A virus that reverses deafness
Health & Science - By Killiad Sinide


Covid-19 cases to shoot up in March
Health & Science - By Mercy Kahenda


Concern over soaring cases of liver failure and liver cancer among Kenyans due to Hepatitis
Health & Science - By Ally Jamah


Government now approves Janssen’s Prostate Cancer drug
Health & Science - By Mireri Junior


Concern over soaring cases of liver failure and liver cancer among Kenyans due to Hepatitis
Health & Science - By Ally Jamah


Why matumbo is good for fertility, pregnancy
Health & Science - By Dr Othieno Joseph


Latest Stories

Hospital swamped as patient numbers swell
Health & Science - By Mercy Kahenda


Covid-19 cases to shoot up in March
Health & Science - By Mercy Kahenda


NMS recruits 600 nurses as it prepares to open four hospitals
Health & Science - By Josephat Thiong'o


139 test Covid-19 positive as cases near 100,000
Health & Science - By Betty Njeru


Covid-19: Three dead as 186 test positive
Health & Science - By Judah Ben-Hur


Africa's COVID-19 case fatality rate surpasses global level
Health & Science - By Reuters


We'll go on with strike, healthcare workers say
Health & Science - By Anyango Otieno and Kirsten Kanja


COVID-19 shots to cost between Sh300 and Sh1100 under African Union vaccine plan
Health & Science - By Reuters


Covid-19: Kenya records 136 new cases as 176 recover
Health & Science - By Judah Ben-Hur


Muslim Council calls on governors to heal health crisis
Health & Science - By Judah Ben-Hur


//

Stay Ahead!

Access premium content only available
to our subscribers.

Or Login With Your Standard Account
Support independent journalism
×
Create An Account
Support independent journalism
I have an account Log in
Reset Password
Support independent journalism
Log in