Jennifer Aniston and Brad Pitt. (Photo/Courtesy)

This time 16 years ago, Jennifer Aniston had just quit Friends to start a much-longed for family with husband Brad Pitt. But instead, Brad fell in love with Angelina Jolie on the set of Mr and Mrs Smith and left Jen in January 2005, leaving her utterly devastated.

And in an unearthed Vanity Fair interview from September that year, Jennifer, then 36, wore her heartbreak on her sleeve when the interviewer broached rumours that Angelina was already pregnant, two months before Jen and Brad's divorce was even finalised.

The Hollywood couple tied the knot in 2000. (Photo/ Courtesy)

ALSO READ: Brad Pitt and Jennifer Aniston are 'back in love'

Describing how the actress looked like she had been "stabbed in the heart," the reporter said Jen cried silently for several minutes, unable to stop the tears rolling down her cheeks before shaking her head, too hurt to give an answer.

As for whether she believed the gossip that Brad and Ange had had a full-blown affair, Jennifer said, “I choose to believe my husband. At this point, I wouldn’t be surprised by anything, but I would much rather choose to believe him."

ALSO READ: Jennifer Aniston 'will love Brad Pitt for the rest of her life'

The line from friends was that he'd wanted to work out what he wanted in life - as a single man - and that he assured Jen, "This is not about another woman." Both Brad and Angelina have always denied any romantic involvement while he was still with Jennifer.

But despite her devastation, Jennifer admitted she "felt lucky to have experienced" her marriage to Brad - which happened 20 years ago today. “I love Brad; I really love him. I will love him for the rest of my life.  He’s a fantastic man. I don’t regret any of it, and I’m not going to beat myself up about it... It was a beautiful, complicated relationship," she said.