How are sleep and sex related? I’ll state the obvious: we most commonly sleep and have sex in the same location – the bedroom. Less obvious but more important is that lack of sleep and lack of sex share some common underlying causes, including stress. Especially important, lack of sleep can lead to sexual problems and a lack of sex can lead to sleep problems. Conversely, a good night’s sleep can lead to a greater interest in sex, and orgasmic sex can result in a better night’s sleep.