TONIGHT: Tottenham heads to Man United; Madrid visits Elche

Tottenham's Harry Kane scores the opening goal from the penalty spot during the English Premier League soccer match between Tottenham Hotspur and Everton at the Tottenham Hotspur Stadium in London, England, Saturday, Oct. 15, 2022. (AP Photo/Kin Cheung)

A look at what's happening in European soccer on Wednesday:

ENGLAND

With the Premier League's top two - Arsenal and Manchester City - inactive this week, third-place Tottenham will look to take advantage when the team heads to Manchester United for the standout match of the midweek round. Tottenham would climb above City into second place, a point behind north London rival Arsenal, with a win. Liverpool looks to back up its victory over City on Sunday with another home win against West Ham. West Ham manager David Moyes has called a match under lights at Anfield the hardest test in soccer. Chelsea protects an unbeaten record under recently hired manager Graham Potter when it heads 5 miles west to Brentford while Newcastle hosts Everton and Southampton visits fellow south-coast club Bournemouth.

SPAIN

Real Madrid will look to defend its three-point Spanish league lead when it visits last-place Elche, the only winless team so far. Madrid is coming off a home win against Barcelona in the first "clasico" of the season. Elche has drawn two in a row, including at Valencia over the weekend. Fourth-place Real Betis visits second-to-last-place Cadiz, which has drawn three consecutive games. Fifth-place Real Sociedad hosts Mallorca, which is winless in three games. Relegation-threatened Valladolid hosts midtable Celta Vigo.

GERMANY

Bayern Munich heads to local rival Augsburg in the second round of the German Cup. It's a potentially tricky game for Bayern, which has lost its last two away games at Augsburg, including a 1-0 defeat in the league last month. Bayern is without Leroy Sane, who has a hamstring injury, and coach Julian Nagelsmann has opted to leave out goalkeeper Manuel Neuer, who has pain in his shoulder, for a third straight game. Among the other games, Borussia Dortmund visits second-division Hannover 96, surprise Bundesliga leader Union Berlin takes on Heidenheim, and Freiburg hosts St. Pauli.