Atletico Madrid thrashed third-tier Rayo Majadahonda 5-0 away in the Copa del Rey to reach the last 16 on Thursday.
A year after Atleti suffered a humiliating 1-0 loss to Unio Esportiva Cornella in the last-32, manager Diego Simeone played a full-strength side against their neighbours, ensuring there was no chance of any surprises this time.
Matheus Cunha, Renan Lodi and Luis Suarez gave Atletico a comfortable lead in the first half. Antoine Griezmann, who came off injured, and Joao Felix wrapped up the win after the break.
"Of course, the Cup is a priority for us," Brazilian striker Matheus Cunha told reporters. "You have to win regardless of who you are. The most important thing is to win and advance."
It was a solid performance by Atletico the day after holders Barcelona and Real Madrid had trouble beating lower-tier sides.
On Wednesday Barca fought back to secure a 2-1 win at third-tier Linares Deportivo, while Real gained revenge for defeat by Alcoyano last year as they won 3-1 with two late goals.
They joined Sevilla, Cadiz, Elche, Athletic Bilbao, Espanyol, Real Sociedad, Valencia, Real Betis, Rayo Vallecano, Mallorca and third-tier Atletico Baleares, who eliminated LaLiga side Celta Vigo with a 2-1 win on Wednesday, in the next round.
Two other top tier sides were eliminated on Thursday by lower division teams. Unai Emery’s Villarreal lost 2-1 at Sporting Gijon and Osasuna went down 1-0 at Girona, with both second-tier clubs also advancing into the last-16.
The draw for the next round will take place at the Spanish Football Federation on Friday. Lower-tier teams will be drawn first to host LaLiga sides after which it will be an open draw.