Globally, Anti-microbial Resistance (AMR) is threatening the very core of modern medicine and sustainability of an effective public health response to infectious diseases. The transformation of our health system should actually be from one that provides easy access to drugs into that which provides easy access to appropriate anti-microbial treatment while reducing the risk of emergence and spread of resistance. Kenya should work for a healthcare system that seeks to address the AMR, and traverses the entire continuum from prevention to care.