HIV has changed. Significant progress has been made in responding to HIV/Aids and science continues to offer new hope. Advances in research and increased availability of potent anti-retroviral treatment (ART), has transformed HIV care from a once life-threatening disease to a now chronic condition. World Aids Day is celebrated on December 1 and provides an opportunity to unite globally in the fight against HIV, raise awareness and show support for victims. This year, the World Aids Day theme is ‘Communities make the difference.’ Milestones in addressing HIV have been achieved when working directly with communities most affected by HIV.