Paris Saint-Germain overcame the absences of injured stars Neymar and Edinson Cavani to win 2-0 away to a stunned Manchester United on Tuesday in the first leg of their Champions League last-16 tie.
Presnel Kimpembe and Kylian Mbappe scored second-half goals for PSG to leave them with one foot in the quarter-finals.
United had Paul Pogba sent off late on as they slumped to their first defeat under interim boss Ole Gunnar Solskjaer.
Zaniolo strikes twice to clinch Roma win over Porto
Two goals from teenager Nicolo Zaniolo earned AS Roma a 2-1 win against Porto in their Champions League last-16 first leg on Tuesday.
The 19-year-old continued his superb breakthrough season by finding the net twice in six second-half minutes to become the youngest Italian to score two goals in a Champions League match.
Porto substitute Adrian Lopez, however, quickly responded with what could prove to be a crucial away goal.
The result ended a five-match winning run in Europe for Porto, who will welcome Roma to the Estadio do Dragao for the second leg on March 6.