Like mania, depression can cause other symptoms as well, but here are seven of the key signs of depression from bipolar disorder:

Feeling sad or hopeless for long periods of time Withdrawing from friends and family Losing interest in activities that you once enjoyed Having a significant change in appetite and weight Suicide prevention Feeling hopeless, sad, or empty Fatigue or loss of energy Physical and mental sluggishness         Sleep problems, concentration and memory problems. Feeling severe fatigue, irritability or lack of energy Having problems with memory, concentration, and decision making Thinking about or attempting suicide, or having a preoccupation with death