Nice have sacked coach Patrick Vieira following a string of poor results, the Ligue 1 club said on Friday.
Nice lost 3-2 at home to Bayer Leverkusen on Thursday in the Europa League, leaving them third in Group C with three points and without any hope of reaching the knockouts.
They have lost their last five competitive games and lie 11th in the Ligue 1 standings.
"Patrick Vieira, who joined the club in the summer of 2018, is no longer head coach of OGC Nice, effective immediately," Nice said in a statement.
"In a meeting conducted after last night’s match, the Nice Board informed Patrick Vieira of their decision to end their collaboration."
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Former Arsenal and France midfielder Vieira, who won the World Cup in 1998, will be replaced by Adrian Ursea.