Arsenal have travelled to Belarus without midfielders Mesut Ozil and Aaron Ramsey.
Ramsey - who has signed a pre-contract with Juventus - has not trained this week while Ozil has been left at home.
The German midfielder was confirmed fit by the north London club before the travelling squad was announced, but was not included.
Ozil took to twitter shortly after the announcement to post pictures of him in training at Arsenal's London Colney base on Wednesday.
He wrote: "Today's winning team. Training fun." He also included hashtags for "team spirit" and "we are the Arsenal."
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Defender Sokratis Papastathopoulos is also missing but Pierre-Emerick Aubameyang and Granit Xhaka are expected to start the Europa Leaugue last-32 tie.
Arsenal boss Unai Emery said: "The players we didn't bring in the squad were because Aaron Ramsey did not train with us and Sokratis only started training on Tuesday and Wednesday, and I don't think it's enough.
"Mesut is the same. Aubameyang, after he was sick, trained this week, and I think he's OK for the match."
Arsenal probable XI: Cech, Mustafi, Koscielny, Monreal, Maitland-Niles, Xhaka, Torreira, Kolasinac, Mkhitaryan, Aubameyang, Iwobi