Paris Saint-Germain overcame the absences of injured stars Neymar and Edinson Cavani to win 2-0 away to a stunned Manchester United on Tuesday in the first leg of their Champions League last-16 tie.
Presnel Kimpembe and Kylian Mbappe scored second-half goals for PSG to leave them with one foot in the quarter-finals.
United had Paul Pogba sent off late on as they slumped to their first defeat under interim boss Ole Gunnar Solskjaer.
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Zaniolo strikes twice to clinch Roma win over Porto
Two goals from teenager Nicolo Zaniolo earned AS Roma a 2-1 win against Porto in their Champions League last-16 first leg on Tuesday.
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The 19-year-old continued his superb breakthrough season by finding the net twice in six second-half minutes to become the youngest Italian to score two goals in a Champions League match.
Porto substitute Adrian Lopez, however, quickly responded with what could prove to be a crucial away goal.
The result ended a five-match winning run in Europe for Porto, who will welcome Roma to the Estadio do Dragao for the second leg on March 6.