Musingu's aim is to top their pool and earn a favourable semi-final draw, potentially avoiding heavyweights in Group B.
"Our plan is simple: finish top of the group, book our place in the semis, and then focus on the bigger prize. We want to make Kakamega and Musingu proud," Lugalia said.
In Group B, defending champions Highway High School remain the team to beat.
The Nairobi-based side faces stiff competition from Rift Valley champions St Joseph Boys Kitale, Coast's Serani High School, and Central Region's Kirangari High School. Kirangari reached the semi-finals last year and narrowly lost 2-1 to Highway.
Despite the presence of strong challengers, the former AFC Leopards and Mmust FC defender believes home support could be the extra push they need to end nearly four decades of heartbreak.
"The rivalry among schools has been intense, sometimes turning bitter, but our boys are ready for the task," Lugalia said.
"There has been a lot of rivalry between schools, and sometimes that brings negative energy.
"But we've talked to the boys. They are focused. We're going to make Kakamega proud. We're going to make Musingu proud."
Kirangari will be hoping to go one better after reaching the semis last year, where they narrowly lost to Highway 2-1. With experience and hunger, they could be one of the surprise packages of the tournament.