Science for Africa Foundation Chief Scientific Officer Dr Evelyn Gitau called for a review of funding flows that continue to mirror donors' priorities rather than Africa's own.
She highlighted the new Good Research Management Practice Standard as part of efforts to strengthen the continent's research ecosystem.
"Africa is not a passive recipient of assistance. We are strengthening our own research systems, building local capacity and shaping our development trajectory on our own terms," she said.
GSMA Head of Africa Angela Wamola turned attention to the role of digital innovation, saying technology can be a force for inclusion or a new driver of inequality.
Drawing from the GSMA-APHRC Enabling Digital Health in Africa report, she emphasised the need for African-led digital health strategies.
"Digital technologies can improve access and inclusion. But partnerships must reinforce African leadership if we are to build sustainable digital health systems that work for everyone," she said.
As the discussions continue, delegates are expected to explore how African-led policy, innovation and research can drive the creation of fairer and more resilient health systems built on the continent's own expertise.
The deliberations are poised to influence how Africa positions itself in a rapidly shifting global health landscape where digital transformation is redefining power and decision-making.