Mesut Ozil looks set to miss Arsenal's key clash at Chelsea.
However, Arsenal's chief creative force missed training on Saturday and is now set to sit out the huge clash at Stamford Bridge with what has been described as a 'muscle' injury.
Arsenal are likely to recall a host of first-team regulars for the short trip to face the Premier League champions.
Alexis Sanchez will feature after playing the whole game on Thursday night, where Theo Walcott (calf) hobbled off. Francis Coquelin (hamstring) and Santi Cazorla (ankle) are definitely out.
Ahead of the London derby, Wenger has rubbished claims that Arsenal have a mental block on the road.
The Gunners have lost both away games this season, including the 4-0 humiliation at Liverpool.
The kicks off at 3.30 pm local time.