Jordyn Woods appeared on Jada Pinkett Smith's Facebook Watch show on Friday, where she gave her side of the story.
She denied cheating but claimed that Tristan had kissed her when she was leaving his home in the early hours of the morning.
She said she originally lied to Khloe about it because she didn't want to cause her pain, and admitted that she shouldn't have been at the party in the first place.
But minutes after the show dropped on Facebook, Khloe took to Twitter to let Jordyn know exactly what she thought of her story.
She said: "Why are you lying @ jordynwoods ?? If you’re going to try and save yourself by going public, INSTEAD OF CALLING ME PRIVATELY TO APOLOGIZE FIRST, at least be HONEST about your story. BTW, You ARE the reason my family broke up!"
She added: "Tristan is equally to blame but Tristan is the father of my child. Regardless of what he does to me, I won’t do that to my daughter. He has been addressing this situation PRIVATELY. If Tristan were to lie publicly about what conspired, then yes I would address him publicly as well"
The following day, Khloe spoke out again, seemingly showing some sympathy for Jordyn.
She said: "This has been an awful week & I know everyone is sick of hearing about it all (as am I). I’m a rollercoaster of emotions & have said things I shouldn’t have. Honestly, Tristan cheating on me & humiliating me wasn’t such a shock as the first time.
Khloe Kardashian has dramatically unfollowed the father of her baby after blaming him for the breakdown of their family.
"What’s been harder & more painful is being hurt by someone so close to me. Someone whom I love & treat like a little sister. But Jordyn is not to be blamed for the breakup of my family. This was Tristan’s fault.
"I have to move on with my life & count my blessings, my family, my health, & my beautiful baby True."
The Keeping Up With The Kardashians star originally kept following her ex Tristan Thompson on Instagram after it emerged that he'd cheated on her with sister Kylie Jenner's best friend Jordyn Woods.
Khloe had unfollowed Jordyn pretty much straight away, and fans questioned why she hadn't done the same to Tristan.
But now, she's given him the same treatment following Jordyn's appearance on Red Table Talk. She has not re-followed Jordyn.