BBC Northern Ireland reporter Julian O'Neill witnessed some of the trouble.
"The smell of smoke hangs heavy in the air as one of three cars hijacked earlier burns in front of a row of police water cannon vehicles," he said.
"Several petrol bombs have rained down on riot police. I saw one bounce off the Perspex shield of one officer and temporarily engulf two others in flames, but mostly it has been bricks and fireworks.
"I've also noticed laser pens being aimed in the direction of police lines."
Some nationalists object to the parade which marks William III's victory at the Battle of the Boyne in 1690.
Earlier, 24 Orange Order marchers completed a parade past the area.
The trouble broke out after Protestant Orangemen, who are members of north Belfast lodges, walked past a row of shops in the Catholic area.
A protest by Catholic residents to show their opposition to the Orangemen walking through the area was held along with a parade by the group Greater Ardoyne Residents Coalition (GARC).
"The Greater Ardoyne Residents Coalition parade was delayed at Estoril Park by agreement due to a public safety issue caused by the significant disorder and a burning vehicle," said Assistant Chief Constable Kerr
"Once this was cleared, the GARC parade continued on to the Crumlin Road.
"Missiles were thrown from both sides as the GARC parade passed the Ardoyne Shop fronts but both the parade and the protest dispersed.